Author

William Sibran

Inserm

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:benchmarking· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:machine learning (classical)· 1 Assay:proteomics· 1 Organism:rat· 1 Approach:statistical model· 1

Frequent Co-Authors

Jean‐Marc TaymansiD· 2 shared Laurine Vandewynckel· 2 shared Marie‐Christine Chartier‐HarliniD· 2 shared Adriana Figueroa GarciaiD· 1 shared Ahmed SolimaniD· 1 shared Alexander Marc ThouiniD· 1 shared Andreas MetousisiD· 1 shared Anna Memou· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersNeuroscience

Jean‐Marc TaymansORCID

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2 papers

Recent·Most cited

Regulation between LRRK2 and PP2A signaling in cellular models of Parkinsons disease

Panagiotis S. Athanasopoulos, Anna Memou, Franz Y. Ho, Ahmed Soliman, Henderikus Pots, Vassiliki Papadopoulou, Felix von Zweydorf, Saiganesh Sriraman, Alexander Marc Thouin, Laurine Vandewynckel, William Sibran, Marie‐Christine Chartier‐Harlin, R. Jeremy Nichols, Elisa Greggio, Jean‐Marc Taymans, , Arjan Kortholt

This study identifies a regulatory feedback loop between LRRK2 and PP2A phosphatases in Parkinson's disease, showing that LRRK2 phosphorylates PP2A to disrupt its function and contribute to neuronal death.

Biochemical Journal · May 14, 2026Peer-reviewedNeuroscience

Multi-cohort, cross-species urinary proteomics reveals signatures of LRRK2 dysfunction in Parkinsons disease

Duc Tung Vu, William Sibran, Andreas Metousis, Laurine Vandewynckel, Basak Eraslan, Liesel Mary Goveas, Ericka C M Itang, Claire Deldycke, Adriana Figueroa Garcia, Réginald Lefebvre, Johannes Müller, Sebastian Virreira Winter, Marie‐Christine Chartier‐Harlin, Jean‐Marc Taymans, Matthias Mann, Özge Karayel

The paper identifies urinary protein signatures linked to LRRK2 dysfunction in Parkinson's disease using multi-cohort proteomics and machine learning, showing cross-species relevance and potential as pharmacodynamic markers.

Molecular Systems Biology · Jan 29, 2026Peer-reviewedSystems Biology