Author

Xiaobo Wang

Center for Life Sciences

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Immunology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Approach:experimental assay· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Jie KangiD· 2 shared Yan Shi· 2 shared Alexey SergushicheviD· 1 shared Alwin J. van der HamiD· 1 shared Arnoud H. de RuiD· 1 shared Barbara Czako· 1 shared Bart EvertsiD· 1 shared Béatrice M. F. WinkeliD· 1 shared

Activity by Year

2018-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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2 shared papersImmunology

Jie KangORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Hierarchical Immune Suppressive Functions of Regulatory T Cells Built on Mechanical Force

Xinyi Liu, Cao Huang, Xiaobo Wang, Jie Kang, Chunlin Zou, Yanni Xu, Longyan Wu, Yan Shi

This study identifies a hierarchical mechanical force-based model of Treg suppression, showing that stable adhesion is required for localized cytokine delivery to dendritic cells.

bioRxiv · May 21, 2026 · PreprintImmunology

O-GlcNAcylation and low glycolysis underpin Th2 polarization by dendritic cells

Leonard R. Pelgrom, Marjolein Quik, José Javier Fernández, Thiago A. Patente, Graham A. Heieis, Alexey Sergushichev, Jie Kang, Xiaobo Wang, Justine Dontaine, Marie-Sophie Fabre, Frank Otto, Alwin J. van der Ham, Lisa W. Bloemberg, Marion H. König, Béatrice M. F. Winkel, , Bart Everts

This study identifies O-GlcNAcylation and reduced glycolysis as key factors in Th2 polarization by dendritic cells, showing their role in immune synapse regulation and TCR signaling.

bioRxiv · Feb 5, 2026 · PreprintImmunology

Eradication of ENO1-deleted Glioblastoma through Collateral Lethality

Yu-Hsi Lin, Nikunj Satani, Naima Hammoudi, Jeffrey J. Ackroyd, Sunada Khadka, Victoria C. Yan, Dimitra K. Georgiou, Yuting Sun, Rafal Zielinski, Theresa Tran, Susana Castro Pando, Xiaobo Wang, David Maxwell, Zhenghong Peng, Federica Pisaneschi, , Florian L. Muller

The paper demonstrates that POMHEX, a modified phosphonate antibiotic, effectively eradicates ENO1-deleted glioblastoma in vivo without causing hemolytic anemia.

bioRxiv · May 25, 2018 · PreprintCancer Biology