Xiaojun Li

Notch1 and Notch2 receptors mediate the prosensory functions of the Notch ligand Jagged1 in the mammalian cochlea

This study identifies Notch1 and Notch2 as mediators of Jagged1's prosensory functions in the cochlea by showing their role in maintaining prosensory progenitors and regulating cell-cycle exit and innervation.

Fungal polysaccharopeptides reduce obesity by richness of specific microbiota and modulation of lipid metabolism

This study shows that fungal polysaccharopeptides reduce obesity through microbiota-dependent and -independent mechanisms, including increasing Akkermansia muciniphila abundance and modulating lipid metabolism.