Author

Xiaole Zhao

Peking University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein structure prediction· 1 Assay:structural biology· 1

Frequent Co-Authors

Hailin PengiD· 1 shared Jiahe ZangiD· 1 shared Lie CheniD· 1 shared Wenjun GuoiD· 1 shared Yikun CheniD· 1 shared Yongmei Tan· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperBiophysics

Hailin PengORCID

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1 paper

Recent·Most cited

Structural Mechanism of TRPC3 Channel Activation by the Moonwalker Mutation

Jiahe Zang, Yongmei Tan, Yikun Chen, Wenjun Guo, Xiaole Zhao, Hailin Peng, Lie Chen

The paper presents structures of hTRPC3 in resting and open states, revealing how the moonwalker mutation activates the channel by disrupting a polar interaction and inducing structural changes.

Cell Discovery · Oct 29, 2026Peer-reviewedBiophysics