Author

Xiaoyi Cheng

Iowa State University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Developmental Biology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 3 Approach:statistical model· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Assay:scRNA-seq· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Clyde Allen CampbelliD· 2 shared Raquel Espín-PalazóniD· 2 shared Sergei R. DoulatoviD· 2 shared A FidanzaiD· 1 shared Aaron D. VinyiD· 1 shared Abigail Gorden· 1 shared Brandon HadlandiD· 1 shared Cole TrapnelliD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersDevelopmental Biology

Clyde Allen CampbellORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Multi-hit STAG2 mutations define a high-risk subset of MDS and reveal convergent evolutionary targeting of cohesin

Eno-obong Udoh, Yi Chen, Matteo D’Addona, Edna M. Stewart, Rong Deng, Felipe de Almeida Sartori, Serhan Ünlü, Zachary Brady, Ruowei Zhu, Xiaoyi Cheng, Viviana Scoca, Jane J Xu, Sergei R. Doulatov, Karl S. Theil, David S. Bosler, , Aaron D. Viny

The paper identifies multi-hit STAG2 mutations in MDS patients, showing they are associated with worse outcomes and suggest convergent evolutionary targeting of the cohesin gene.

bioRxiv · Sep 3, 2026 · PreprintCancer Biology

Developmental regulation of endothelial-to-hematopoietic transition from induced pluripotent stem cells

Rachel Wellington, Xiaoyi Cheng, Shuvra Dutta, Clyde Allen Campbell, Cole Trapnell, Raquel Espín-Palazón, Brandon Hadland, Sergei R. Doulatov

The paper maps single-cell dynamics of endothelial-to-hematopoietic transition from iPSCs and identifies FGF signaling modulation to improve hematopoietic output.

Stem Cell Reports · Sep 23, 2025Peer-reviewedDevelopmental Biology

Nod1-dependent NF-kB activation initiates hematopoietic stem cell specification in response to small Rho GTPases

Xiaoyi Cheng, Radwa Barakat, Giulia Pavani, Masuma Khatun Usha, Rodolfo Calderon, Elizabeth M. Snella, Abigail Gorden, Yudi Zhang, Paul J. Gadue, Deborah L. French, Karin S. Dorman, A Fidanza, Clyde Allen Campbell, Raquel Espín-Palazón

This paper identifies the NOD1-RIPK2-NFkB axis as a critical inflammatory pathway for hematopoietic stem cell specification from human pluripotent stem cells.

Nature Communications · Nov 23, 2023Peer-reviewedDevelopmental Biology