Author

Xiaoying Lian

University of South Carolina

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Assay:metagenomics· 2 Organism:bacteria (other)· 1 Research Focus:host-pathogen & immune response· 1 Assay:metabolomics· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Ethan A. OlderiD· 3 shared Jie LiiD· 3 shared Andrew Campbell· 2 shared Conor PulliamiD· 2 shared Dan XueiD· 2 shared Daping FaniD· 2 shared Yuzhen WangiD· 2 shared Armando SardiiD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersBiochemistry

Ethan A. OlderORCID

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Author profile →

3 papers

Recent·Most cited

Human gut commensal Alistipes timonensis modulates the host lipidome and delivers anti-inflammatory outer membrane vesicles to suppress colitis in an Il10-deficient mouse model

Ethan A. Older, Mary K. Mitchell, Andrew Campbell, Xiaoying Lian, Michael Madden, Yuzhen Wang, Lauren E. van de Wal, Thelma Zaw, Brandon N. VanderVeen, Rodney Tatum, E. Angela Murphy, Yan-Hua Chen, Daping Fan, Melissa Ellermann, Jie Li

This study shows that Alistipes timonensis colonization in Il10-deficient mice delays colitis by altering the host lipidome and delivering anti-inflammatory outer membrane vesicles containing immunomodulatory lipids.

Gut Microbes · Jun 11, 2025Peer-reviewedBiochemistry

Discovery and Biosynthesis of Sulfenicin and Its New-to-Nature Acylsulfenic Acid Functional Group

Dan Xue, Hongbin Zou, Yanping Qiu, Wei Lv, Michael D. Madden, Mingming Xu, Xiaoying Lian, Conor Pulliam, Ethan A. Older, Lukuan Hou, Andrew Campbell, Tristan de Rond, Takayoshi Awakawa, Chunhua Yuan, Bradley S. Moore, Jie Li

The paper discovers sulfenicin, a novel natural product with a unique acylsulfenic acid functional group, and identifies the enzymes involved in its biosynthesis.

Nature Chemistry · May 20, 2025Peer-reviewedBiochemistry

Discovery of A Chimeric Polyketide Family as Cancer Immunogenic Chemotherapeutic Leads

Dan Xue, Mingming Xu, Michael D. Madden, Xiaoying Lian, Ethan A. Older, Conor Pulliam, Yvonne Y. Hui, Zhuo Shang, Gourab Gupta, Manikanda Raja Keerthi Raja, Yuzhen Wang, Armando Sardi, Yaoling Long, Hexin Chen, Daping Fan, , Jie Li

This paper discovers a new class of cancer immunogenic chemotherapeutic leads called aspercyclicins through a high-throughput screening platform and structural elucidation techniques.

Journal of the American Chemical Society · Dec 28, 2024Peer-reviewedBiochemistry