Author

Gourab Gupta

University of South Carolina

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:metabolomics· 1

Frequent Co-Authors

Hexin CheniD· 3 shared Conor PulliamiD· 2 shared Dan XueiD· 2 shared Daping FaniD· 2 shared Jie LiiD· 2 shared Manikanda Raja Keerthi RajaiD· 2 shared Mingming XuiD· 2 shared Zhuo ShangiD· 2 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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3 shared papersMicrobiology

Hexin ChenORCID

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Author profile →

3 papers

Recent·Most cited

Genome Mining of the Tumor Microbiome Reveals Biosynthetic Diversity and Potential Tumor-modulating Metabolites

Conor Pulliam, Mingming Xu, Katherine S. Holandez-Lopez, Dan Xue, Zhuo Shang, Gourab Gupta, Olivia E. Dioli, Leilei Gou, Jennifer S. Brodbelt, Xuefeng Peng, Hexin Chen, Jie Li

The paper surveys the biosynthetic potential of the human tumor microbiome, identifying novel metabolites and their potential roles in tumor pathology.

bioRxiv · Aug 11, 2026 · PreprintMicrobiology

Host-derived Interleukin 1α induces an immunosuppressive tumor microenvironment via regulating monocyte-to-macrophage differentiation

Manikanda Raja Keerthi Raja, Gourab Gupta, Grace Atkinson, Katie L. Kathrein, Alissa Richmond Armstrong, Robert Michael Gower, Igor B. Roninson, Eugenia V. Broude, Mengqian Chen, Hao Ji, Chang‐Uk Lim, Hongjun Wang, Daping Fan, Peisheng Xu, Jie Li, , Hexin Chen

This study shows that host-derived IL-1α promotes an immunosuppressive tumor microenvironment by regulating monocyte-to-macrophage differentiation in breast cancer.

npj Breast Cancer · Jan 17, 2026Peer-reviewedCancer Biology

Discovery of A Chimeric Polyketide Family as Cancer Immunogenic Chemotherapeutic Leads

Dan Xue, Mingming Xu, Michael D. Madden, Xiaoying Lian, Ethan A. Older, Conor Pulliam, Yvonne Y. Hui, Zhuo Shang, Gourab Gupta, Manikanda Raja Keerthi Raja, Yuzhen Wang, Armando Sardi, Yaoling Long, Hexin Chen, Daping Fan, , Jie Li

This paper discovers a new class of cancer immunogenic chemotherapeutic leads called aspercyclicins through a high-throughput screening platform and structural elucidation techniques.

Journal of the American Chemical Society · Dec 28, 2024Peer-reviewedBiochemistry