Author

Xiaoyu Sun

State Key Laboratory of Experimental Hematology

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Biology Disciplines

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Genetics· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:C. elegans· 1 Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Research Focus:perturbation response prediction· 1

Frequent Co-Authors

Aibin HeiD· 1 shared David GemsiD· 1 shared Dawei HuoiD· 1 shared Haiqing XiongiD· 1 shared Hannah ChapmaniD· 1 shared Huimin ZhengiD· 1 shared Isadora RawlinsoniD· 1 shared Kuei Ching HsiungiD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperGenetics

Aibin HeORCID

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2 papers

Recent·Most cited

Effects of knockdown of autophagy pathway genes on C. elegans longevity are highly condition dependent

Kuei Ching Hsiung, Hannah Chapman, Xiaoya Wei, Xiaoyu Sun, Isadora Rawlinson, David Gems

This study shows that autophagy gene knockdown in C. elegans affects lifespan in a highly condition-dependent manner, with variable outcomes based on genetic background, temperature, and experimental conditions.

bioRxiv · Jul 28, 2025 · PreprintGenetics

Generation and Validation of Versatile Inducible CRISPRi Embryonic Stem Cell and Mouse Models

Rui Li, Xianyou Xia, Xing Wang, Xiaoyu Sun, Zhongye Dai, Dawei Huo, Huimin Zheng, Haiqing Xiong, Aibin He, Xudong Wu

This paper develops an inducible CRISPRi system in mouse embryonic stem cells and generates a knockin mouse model for gene function studies.

PLoS Biology · Nov 30, 2020Peer-reviewedGenetics