Author

Xin Cai

The University of Texas Southwestern Medical Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Alexandria Markovitz· 1 shared Bing Wu· 1 shared Charles NgiD· 1 shared Christopher Austin KlebanoffiD· 1 shared Chun Dai· 1 shared Craig B. ThompsoniD· 1 shared Daniel N. WeinbergiD· 1 shared Dayi LiiD· 1 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperImmunology

Alexandria Markovitz

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2 papers

Recent·Most cited

Mitochondrial ATP production promotes T cell differentiation and function by regulating chromatin accessibility

Charles Ng, Tak Shun Fung, Dayi Li, Korbinian Nepomuk Kropp, Luis F. Somarribas Patterson, Alexandria Markovitz, Daniel N. Weinberg, Olivia Jones, Ji-Young Kim, Guoan Zhang, Richard P. Koche, Mara Monetti, Huayuan Tang, Yun He, Zhengshuang Xu, , Craig B. Thompson

This study shows that mitochondrial ATP production, induced by D-α-hydroxybutyrate, promotes T cell differentiation and function by regulating chromatin accessibility and gene expression.

bioRxiv · Mar 28, 2026 · PreprintImmunology

Application of clinical genomic sequencing among Chinese advanced cancer patients to guide precision medicine decisions

Shunchang Jiao, Yuxian Bai, Chun Dai, Xiaoman Xu, Xin Cai, Guan Wang, Jinwang Wei, Bing Wu, Wending Sun, Qiang Xu

This study evaluates the impact of clinical genomic sequencing (CWES) on treatment outcomes for Chinese stage IV cancer patients, finding improved progression-free survival in those following CWES recommendations.

bioRxiv · Dec 19, 2018 · PreprintCancer Biology