Author

Charles Ng

Memorial Sloan Kettering Cancer CenterORCID 0000-0003-3696-1498Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Charles Ng1 paper · NewYork–Presbyterian Hospital

Biology Disciplines

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Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1

Frequent Co-Authors

Craig B. ThompsoniD· 2 shared Dayi LiiD· 2 shared Olivia JonesiD· 2 shared Tak Shun FungiD· 2 shared Alexandria Markovitz· 1 shared Christopher Austin KlebanoffiD· 1 shared Daniel N. WeinbergiD· 1 shared Elizabeth M. SteinertiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersImmunology

Craig B. ThompsonORCID

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintMar 28, 2026

Mitochondrial ATP production promotes T cell differentiation and function by regulating chromatin accessibility

Charles Ng, Tak Shun Fung, Dayi Li…·Craig B. Thompson

This study shows that mitochondrial ATP production, induced by D-α-hydroxybutyrate, promotes T cell differentiation and function by regulating chromatin accessibility and gene expression.

DOI 10.64898/2026.03.27.714789

mousebulk RNA-seq

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Cell BiologyMolecular CellPeer-reviewedOct 24, 2023

Lactate activates the mitochondrial electron transport chain independent of its metabolism

Xin Cai, Charles Ng, Olivia Jones…·Craig B. Thompson

This study shows lactate activates the mitochondrial electron transport chain without being metabolized, suppressing glycolysis and enhancing oxidative phosphorylation in various cell types.

269 citationstop 1%

humanmetabolomics

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