Author

Xing Lou

Yale University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Genomics· 1 Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:cell-cell communication· 3 Research Focus:differential expression· 3 Organism:human· 3 Organism:mouse· 3 Assay:spatial transcriptomics· 3 Approach:statistical model· 3 Approach:experimental assay· 2

Frequent Co-Authors

Rong FaniD· 4 shared Mei ZhongiD· 3 shared Arnar GeirssoniD· 2 shared Dejiang WangiD· 2 shared Di ZhangiD· 2 shared Fu GaoiD· 2 shared Alejandro SifrimiD· 1 shared Ana NikolićiD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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4 shared papersCell Biology

Rong FanORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Decoding and Targeting Coordinated CDKN1A and CDKN2A Senescence Programs in ECM-Dominant Cardiovascular Pathologies

Fu Gao, Anthony A. Fung, D Zhang, Xing Lou, Jungmin Nam, Mingyu Yang, Xiaolong Tian, Negin Farzad, Dejiang Wang, Gaocai Li, Xiangjun Di, Shujie He, Mei Zhong, Arnar Geirsson, Liu Yang, Rong Fan

This study identifies ECM-dominant cardiovascular diseases as driven by coordinated CDKN1A and CDKN2A senescence programs in fibroblasts and shows senolytic treatments improve cardiac function.

bioRxiv · Jun 20, 2026 · PreprintCell Biology

Cross-Species Multi-Omics Profiling Identifies Conserved Activated Valvular Interstitial Cell Population Driving Myxomatous Mitral Valve Degeneration

Fu Gao, Ian Mason, Mingze Dong, Yue Lu, Di Zhang, Xing Lou, Irbaz Hameed, Mingyu Yang, Mei Zhong, Marcus Krane, Giovanni Ferrari, George Tellides, Yang Liu, Rong Fan, Arnar Geirsson

The paper identifies a conserved activated valvular interstitial cell population across species and disease types that drives myxomatous mitral valve degeneration.

bioRxiv · Mar 25, 2026 · PreprintMolecular Biology

Spatial epigenomic niches underlie glioblastoma cell state plasticity

Sam Kint, Subhi Talal Younes, Shuozhen Bao, Gretchen Long, David Wouters, Erin L. Stephenson, Xing Lou, Mei Zhong, Di Zhang, Graham Su, Archibald Enninful, Mingyu Yang, Huey‐Miin Chen, Katrina I Ellestad, Colleen Anderson, , Marco Gallo

This study identifies two epigenetically-defined spatial niches in glioblastoma that influence cell state plasticity through local and long-range molecular signals.

bioRxiv · May 9, 2025 · PreprintGenomics

Spatial dynamics of mammalian brain development and neuroinflammation by multimodal tri-omics mapping

Di Zhang, Leslie A. Kirby, Yingxin Lin, Mengyi Song, Li Wang, Lijun Wang, Shigeaki Kanatani, Tony Jimenez-Beristain, Yonglong Dang, Mei Zhong, Petra Kukanja, Shaohui Wang, Xinyi Chen, Fu Qiang Gao, Dejiang Wang, , Rong Fan

Spatial tri-omic sequencing (DBiT ARP-seq and DBiT CTRP-seq) and CODEX imaging map chromatin, RNA, and protein dynamics across mammalian brain development and lysolecithin-induced neuroinflammation.

bioRxiv · Jul 28, 2024 · PreprintNeuroscience