Alpha Spatial: Language-guided prediction of single-cell spatial gene expression from histology
XI YANG, Ziyi Guo, XUYUAN GUO, Wan Wang, Bowen Bai, Xingran Liu, Chao Zhang, Yufei He, YUNCAI LIU
Alpha Spatial predicts single-cell gene expression from histology using language-guided models, improving accuracy with matched biological context and outperforming existing methods in breast cancer analysis.
bioRxiv · Oct 15, 2026 · PreprintBioinformatics