BioinformaticsbioRxivPreprint
Alpha Spatial: Language-guided prediction of single-cell spatial gene expression from histology
XI YANG, Ziyi Guo, XUYUAN GUO…·YUNCAI LIU
Alpha Spatial predicts single-cell gene expression from histology using language-guided models, improving accuracy with matched biological context and outperforming existing methods in breast cancer analysis.
DOI 10.64898/2026.10.08.756444