Author

Xinyi Jiang

Fudan University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Biology Disciplines

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Bioinformatics· 1 Cell Biology· 1 Molecular Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Approach:deep learning· 2 Organism:human· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1

Frequent Co-Authors

Qiang HuangiD· 2 shared Alexia van RinsumiD· 1 shared Christiane OttiD· 1 shared Daosheng Huang· 1 shared Deli ZhangiD· 1 shared Fang Ye· 1 shared Guoji GuoiD· 1 shared Haide Chen· 1 shared

Activity by Year

2017-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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2 shared papersBioinformatics

Qiang HuangORCID

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Author profile →

4 papers

Recent·Most cited

A novel and robust method for assessing mitochondrial (dys)function in healthy and diseased frozen cardiac tissue

Liangyu Hu, Alexia van Rinsum, Rocco Caliandro, Qi Xi, Shuxiu Fan, Xinyi Jiang, Jur Massop, Melissa Bekkenkamp‐Grovenstein, Christiane Ott, Tilman Grune, Melissa A.E. van de Wal, Werner J.H. Koopman, Marcel Giesbers, Monika M Gladka, Jaap Keijer, Deli Zhang

This paper introduces TSIT, a method to assess mitochondrial function in frozen cardiac tissue, showing comparable results to fresh samples and detecting dysfunction in various mouse models and human samples.

Communications Biology · Aug 19, 2025Peer-reviewedPhysiology

Deep generative design of neutralizing nanobodies againstSARS-CoV-2 variants

Liyun Huo, Tian Tian, Yanqin Xu, Qin Qin, Xinyi Jiang, Qiang Huang

This study designs nanobodies against SARS-CoV-2 variants using a deep generative model, identifying two neutralizing candidates.

bioRxiv · Oct 29, 2024 · PreprintBioinformatics

Directed-evolution mutations of adenine base editor ABE8e improve its DNA-binding affinity and protein stability

Haixia Zhu, Xinyi Jiang, Lei Wang, Qin Qin, Menghua Song, Qiang Huang

This study identifies how directed-evolution mutations in ABE8e enhance DNA-binding affinity and protein stability, improving its base editing activity.

bioRxiv · May 9, 2023 · PreprintMolecular Biology

Mapping Human Hematopoietic Hierarchy At Single Cell Resolution By Microwell-seq

Shujing Lai, Yang Xu, Wentao Huang, Mengmeng Jiang, Haide Chen, Fang Ye, Renying Wang, Yunfei Qiu, Xinyi Jiang, Daosheng Huang, Jie Mao, Yanwei Li, Yingru Lu, Jin Xie, Qun Fang, , Guoji Guo

The paper develops Microwell-seq, a high-throughput scRNA-seq platform, to construct a single-cell resolution transcriptome atlas of human hematopoietic differentiation, revealing a revised hierarchy without oligopotent progenitors.

bioRxiv · Apr 13, 2017 · PreprintCell Biology