Xinyi Wang

SpiraMed: A Stereotactic Helix-based Therapy Delivery system for the Human Brain

SpiraMed improves brain therapy delivery by using a helical catheter system that enhances coverage and reduces reflux and bleeding risks.

Targeting Microbial Bile Salt Hydrolase Reprograms Bile Acid Metabolism and Ameliorates Metabolic Dysfunction-Associated Steatohepatitis in Mice

This study shows that the BSH inhibitor GR-7 reduces steatosis, inflammation, and fibrosis in a mouse model of MASH through bile acid metabolism reprogramming and immune modulation.

Contextual Evaluation of MicroRNA Sequencing Data Harmonization: Performance in Sample Clustering

The paper evaluates microRNA sequencing data harmonization by assessing its impact on sample clustering, showing that harmonization can partially restore clustering accuracy depending on method and settings.

Alcohol impacts an fMRI marker of neural inhibition in humans and rodents.

This study examines how acute alcohol consumption affects neural inhibition in both rats and humans using the Hurst exponent as an fMRI marker, finding reduced inhibition in both species.

Antarctic marine microplastics reveals environmental persistence and rapid evolution of Candida auris

The paper isolates Candida auris from Antarctica, identifies cold-adapted traits, and links mutator phenotypes to rapid evolution and drug resistance in global C. auris clades.

Aberrant Temporal-spatial Patterns to Sad expressions in Major Depressive Disorders via Hidden Markov Model

This study uses a hidden Markov model to analyze neural activity patterns in MDD patients and healthy controls during a sad expression task, finding altered temporal-spatial activation patterns associated with depression severity.