An in vivo fitness gene of Toxoplasma, MIC11, is essential for PLP1-mediated egress from host cells
Yuta Tachibana, Xue Gu, Miwa Sasai, Hidetaka Kosako, Eizo Takashima, Daron M. Standley, Vern B. Carruthers, Dominique Soldati‐Favre, Masahiro Yamamoto
The paper identifies MIC11 as an essential gene for Toxoplasma gondii egress, showing it interacts with PLP1 to disrupt host cell membranes.
Nature Communications · Apr 4, 2026Peer-reviewedMicrobiology