Aldh3a1-mediated detoxification of reactive aldehydes contributes to distinct muscle responses to Amyotrophic Lateral Sclerosis progression
Ang Li, Li Dong, Xuejun Li, Jianxun Yi, Jo-Yu Wu, Jianjie Ma, Jingsong Zhou
This study identifies Aldh3a1's role in protecting muscles from ALS progression by detoxifying reactive aldehydes, showing differential expression and functional importance across muscle types.
Free Radical Biology and Medicine · Mar 12, 2026Peer-reviewedCell Biology