Autolamellasomes: Linking Autophagy-Dependent ER Degradation to Whorled Lysosome Biogenesis
Di Lu, Rouxuan Zhang, Wanjing Shi, Delin Zhan, Yuntian Yang, Xulin Sun, Han Zhang, Ying Li, Xueming Li, Li‐Rong Yu
The paper identifies autolamellasomes as a form of ER remodeling mediating bulk ER degradation under mTOR inhibition, linking it to lysosomal membrane homeostasis and aging.
bioRxiv · Nov 16, 2025 · PreprintCell Biology