Author

Xuyu Yang

National Institutes of Health

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Neuroscience· 1

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Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:mouse· 1 Assay:proteomics· 1

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Daniel T. Abebe· 1 shared Lan XiaoiD· 1 shared Pranav SharmaiD· 1 shared Y. Peng LohiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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4 top collaborators · 6 mutual co-author links

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1 shared paperNeuroscience

Daniel T. Abebe

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1 paper

Recent·Most cited

Neurotrophic Factor-α1/carboxypeptidase E regulates critical protein networks to rescue neurodegeneration, defective synaptogenesis and impaired autophagy in Alzheimer's Disease mice

Lan Xiao, Pranav Sharma, Xuyu Yang, Daniel T. Abebe, Y. Peng Loh

This paper investigates the effects of NF-1/CPE gene therapy in AD mice, finding it prevents memory loss and reverses pathology by modulating protein networks involved in synaptogenesis, autophagy, and tau/Aβ accumulation.

Translational Neurodegeneration · Nov 26, 2025Peer-reviewedNeuroscience