Reversible auto-inhibitory regulation of Escherichia coli metallopeptidase BepA for selective β-barrel protein degradation
Y. Daimon, S.-i. Narita, R. Miyazaki, Y. Hizukuri, H. Mori, Y. Tanaka, T. Tsukazaki, Y. Akiyama
This study investigates how the α9/H246 loop in BepA regulates its protease activity, revealing a histidine switch mechanism that controls degradation of misassembled LptD.
bioRxiv · Jul 7, 2020 · PreprintBiochemistry