BiochemistrybioRxivPreprint
Reversible auto-inhibitory regulation of Escherichia coli metallopeptidase BepA for selective β-barrel protein degradation
Y. Daimon, S.-i. Narita, R. Miyazaki…·Y. Akiyama
This study investigates how the α9/H246 loop in BepA regulates its protease activity, revealing a histidine switch mechanism that controls degradation of misassembled LptD.
DOI 10.1101/2020.07.07.192476