Author

Y. Ishigami

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Ayaz· 1 shared A. R. Krainer· 1 shared C. Marti-Gomez· 1 shared D. M. McCandlish· 1 shared J. B. Kinney· 1 shared M. Kooshkbaghi· 1 shared M. S. Wong· 1 shared S. Hanson· 1 shared

Activity by Year

2022-2022 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperBiophysics

A. Ayaz

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1 paper

Recent·Most cited

Specificity, synergy, and mechanisms of splice-modifying drugs

Y. Ishigami, M. S. Wong, C. Marti-Gomez, A. Ayaz, M. Kooshkbaghi, S. Hanson, D. M. McCandlish, A. R. Krainer, J. B. Kinney

This study develops quantitative models to understand how splice-modifying drugs work, showing drug-specific mechanisms and revealing widespread drug synergy and cooperativity.

bioRxiv · Dec 30, 2022Biophysics