MicrobiologybioRxiv
Experimental and mathematical insights on the interactions between poliovirus and a defective interfering genome
R. Andino, Y. Shirogane, E. Rousseau…·S. Bianco
The paper investigates how defective interfering genomes affect wild-type poliovirus replication using a mathematical model and experimental data, finding that DI replication and encapsidation are key factors in determining viral competition outcomes.
DOI 10.1371/journal.ppat.1009277