Long term sterile immunity induced by an adjuvant-containing live-attenuated AIDS virus
T. Okamura, Y. Shimizu, T. Kanuma, Y. Tsujimura, M. N. Asaka, K. Matsuo, T. Yamamoto, Y. Yasutomi
This study constructs a live-attenuated SHIV expressing Ag85B and shows it induces strong sterile immunity against pathogenic SHIV in macaques.
bioRxiv · May 22, 2020 · PreprintImmunology