Author

T. Okamura

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Assay:bulk RNA-seq· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

K. Fujio· 2 shared K. Yamamoto· 2 shared M. Nakano· 2 shared M. Ota· 2 shared Y. Yasutomi· 2 shared A. Hoshino· 1 shared A. Kanatani· 1 shared A. Saito· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersImmunology

K. Fujio

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Impact of perinatal maternal docosahexaenoic acid-containing phospholipid synthesis on offspring growth and neurological symptoms

A. Kanatani, D. Hishikawa, K. Nagata, F. Hamano, K. Nakano, T. Okamura, T. Shimizu, H. Shindou, T. Nagamatsu, K. Yanagida

This study shows that maternal DHA-PL synthesis during fetal development affects offspring neuropsychiatric outcomes, but not postnatal growth or brain size.

bioRxiv · Jan 6, 2024 · PreprintBiochemistry

An engineered ACE2 decoy broadly neutralizes Omicron subvariants and shows therapeutic effect in SARS-CoV-2-infected cynomolgus macaques

E. Urano, Y. Itoh, T. Suzuki, T. Sasaki, J.-i. Kishikawa, K. Akamatsu, Y. Higuchi, Y. Sakai, T. Okamura, S. Mitoma, F. Sugihara, A. Takada, M. Kimura, M. Hirose, T. Sasaki, , T. Okamoto

This paper shows an engineered ACE2 decoy neutralizes Omicron subvariants and is effective in treating SARS-CoV-2 infection in macaques.

bioRxiv · Dec 29, 2022 · PreprintMicrobiology

Autotaxin is a Potential Link between Genetic Risk Factors and Pathogenesis of Systematic Lupus Erythematosus in Plasmacytoid Dendritic Cells

Y. Tsuchida, H. Shoda, M. Nakano, M. Ota, T. Okamura, K. Yamamoto, M. Kurano, Y. Yatomi, K. Fujio, T. Sawada

The paper investigates autotaxin's role in SLE by analyzing transcriptome and eQTL data, finding elevated autotaxin levels and its association with interferon-related genes in pDCs.

bioRxiv · Oct 25, 2021 · PreprintImmunology

Immune cell multi-omics analysis reveals contribution of oxidative phosphorylation to B cell functions and organ damage of lupus

Y. Takeshima, Y. Iwasaki, M. Nakano, Y. Narushima, M. Ota, Y. Nagafuchi, S. Sumitomo, T. Okamura, K. B. Elkon, K. Ishigaki, A. Suzuki, Y. Kochi, K. Yamamoto, K. Fujio

The paper identifies oxidative phosphorylation (OXPHOS) as a key driver in SLE B cells, linking mitochondrial dysfunction to immune signaling and organ damage.

bioRxiv · Oct 8, 2021 · PreprintImmunology

Long term sterile immunity induced by an adjuvant-containing live-attenuated AIDS virus

T. Okamura, Y. Shimizu, T. Kanuma, Y. Tsujimura, M. N. Asaka, K. Matsuo, T. Yamamoto, Y. Yasutomi

This study constructs a live-attenuated SHIV expressing Ag85B and shows it induces strong sterile immunity against pathogenic SHIV in macaques.

bioRxiv · May 22, 2020 · PreprintImmunology