LNP-CpG: deploy the self-adjuvant role of mRNA vaccines
Ning Luan, Han Cao, Xiaolong Zhang, Fengmei Yang, Caixia Lu, Yang He, Qianqian Li, Yanwei Bi, Zhanlong He, Shengtao Fan, Liu Liu, Shaogui Wan, Cunbao Liu
This study demonstrates that LNP-CpG enhances immunogenicity of subunit vaccines in mice and non-human primates, outperforming existing vaccines and showing broad applicability across vaccine platforms.
bioRxiv · Aug 23, 2026 · PreprintImmunology