Yang Xie

SpatialOmicsLab: an integrated research environment for AI co-scientists in spatial transcriptomics

SpatialOmicsLab provides an integrated environment with AI tools for spatial transcriptomics analysis, outperforming expert workflows in multiple tasks.

Simultaneous multi-area recordings in macaque frontoparietal cortex during a manual object-interaction task

This paper presents a dataset of neural and kinematic recordings from a macaque performing complex hand-object interactions, showing variation in decoding performance across algorithms and channel availability.

Attention Guided Mechanism Interpretable Drug-Gene Interaction (MIDI) Modeling for Cancer Drug Response Prediction and Target Effect Explanation

This paper introduces MIDI, a model that predicts cancer drug response and explains drug-target interactions using an attention mechanism, outperforming existing methods in prediction and interpretability.

Construction of a low-temperature degrading synthetic bacterial community of corn straw

The paper constructs a synthetic bacterial community that efficiently degrades corn straw at low temperatures, achieving higher degradation rates in both solid-state and liquid-state fermentation.

Cmai: Predicting Antigen-Antibody Interactions from Massive Sequencing Data

Cmai predicts antigen-antibody interactions from high-throughput BCR sequencing data, revealing immune responses to tumor antigens and ICI treatment outcomes.

The immune vulnerability landscape of the 2019 Novel Coronavirus, SARS-CoV-2

The paper predicts T cell and B cell immunogenic epitopes of SARS-CoV-2 using genomic data and compares them with SARS-CoV and MERS-CoV to identify immune vulnerability patterns.