Breast cancer ovarian metastases show increased activity of GPCR pathways
Laura Savariau, Ye Qin, Osama Shiraz Shah, Ahmed Basudan, Chris Merkel, Saumya Dushyant Sisoudiya, Smruthy Sivakumar, Ethan S. Sokol, Olivia McGinn, Zheqi Li, Tiantong Liu, Nilgun Tasdemir, Pooja Tallapaneni, Lan Gardner Coffman, Esther Elishaev, , Steffi Oesterreich
The paper identifies increased GPCR pathway activity in breast cancer ovarian metastases and links it to migration and F-actin reorganization through CaSR.
bioRxiv · Jul 31, 2026 · PreprintCancer Biology