Zheqi Li

The paper identifies increased GPCR pathway activity in breast cancer ovarian metastases and links it to migration and F-actin reorganization through CaSR.

This study shows that ER-positive ILC xenograft models replicate metastatic patterns and endocrine response of human invasive lobular breast carcinoma.

The paper describes the Hope for Others rapid autopsy program for metastatic breast cancer, detailing its protocols, sample collection, and findings on metastasis research and model development.

EstroGene2.0 is a multi-omic database that compiles data on estrogen receptor responses and resistance in breast cancer, revealing diverse transcriptomic changes and identifying key targets.

The paper introduces MICA, a method to detect multi-class biomarkers across multiple transcriptomic studies, showing improved accuracy and biological insights in both bulk and single-cell data.

This study shows ER fusion proteins in breast cancer cell lines drive ligand-independent pro-oncogenic pathways, with subtype- and fusion-specific effects.

This study shows that Hrq1/RECQL4 regulates DNA intrastrand crosslink repair and its misregulation contributes to genomic instability in cancer.