Yi Zhao

NuGraph: Graph-Based Reasoning over 3D Primitives for Nucleus Segmentation Correction

This paper introduces a graph-based framework for correcting nucleus segmentation errors in 3D reconstructions, achieving high accuracy on brain-scale benchmarks.

Pharmacological recruitment of a VTA glutamatergic arousal circuit by the natural product BN3 drives broad-spectrum emergence from general anesthesia

The paper identifies BN3 as a broad-spectrum agent that accelerates emergence from general anesthesia by targeting a VTA glutamatergic arousal circuit.

Alzheimer's Disease Sequencing Project Release 4 Whole Genome Sequencing Dataset

The paper provides a whole-genome sequencing dataset of 36,361 ADSP participants, including variant annotations, phenotypes, and a linkage disequilibrium panel for Alzheimer's Disease research.

MdLRR-RLK1-MdATG3 module enhances the resistance of apples to abiotic stress via autophagy

The paper identifies a module involving MdLRR-RLK1 and MdATG3 that enhances apple resistance to abiotic stress through autophagy.

GeneCompass: Deciphering Universal Gene Regulatory Mechanisms with Knowledge-Informed Cross-Species Foundation Model

GeneCompass is a cross-species foundation model pre-trained on single-cell transcriptomes from human and mouse, integrating biological knowledge to improve gene regulatory mechanism understanding and downstream tasks.

Activated fibroblasts drive cellular interactions in end-stage pediatric hypertrophic cardiomyopathy

This study identifies distinct cellular processes in end-stage pediatric HCM using single-nucleus RNA sequencing, highlighting activated fibroblasts and stressed cardiomyocytes.