Author

Yu Gan

Sichuan UniversityPrimary ORCID profile (0009-0006-2193-1199 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

Yu GaniD1 paper · Second Affiliated Hospital of Guangzhou Medical University

Biology Disciplines

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Biochemistry· 1 Genetics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:differential expression· 1 Assay:electronic health records· 1 Research Focus:gene regulatory network inference· 1 Approach:machine learning (classical)· 1 Organism:mouse· 1 Organism:rat· 1

Frequent Co-Authors

Bowen KeiD· 2 shared Jin LiuiD· 2 shared Ao Hai· 1 shared Bilal AhmadiD· 1 shared Buyi Xu· 1 shared Fan ZhangiD· 1 shared Fuchun ZhangiD· 1 shared Guotian LiuiD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersNeuroscience

Bowen KeORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Pharmacological recruitment of a VTA glutamatergic arousal circuit by the natural product BN3 drives broad-spectrum emergence from general anesthesia

Ran Ji, Yi Zhao, Zhenbo Huang, Xuehan Li, Yuehua Chen, Yu Gan, Tian Zhang, Ao Hai, Shirong Lai, Tianyou Liu, Yudong Yin, Yuhao Sun, Yuan Yu, Buyi Xu, Jin Liu, Bowen Ke

The paper identifies BN3 as a broad-spectrum agent that accelerates emergence from general anesthesia by targeting a VTA glutamatergic arousal circuit.

bioRxiv · Feb 18, 2026 · PreprintNeuroscience

TRPV4 Inhibition by a Natural Product Mediates Analgesia

Zhen Yuan, Jie Qiu, Shiliang Li, Hanqing Zhao, Na Chen, Shanshan Ruan, Yu Gan, Jiawen Wang, Tianyu Ye, Wenjie Liao, Ziyuan Li, Yanyan Diao, Lili Zhu, Zhenjiang Zhao, Rui Wang, , Bowen Ke

This study identifies AH001 as a potent TRPV4 inhibitor, revealing its mechanism and demonstrating its analgesic effects in pain models.

bioRxiv · Jan 5, 2026 · PreprintBiochemistry

Integrative genomics reveals the polygenic basis of seedlessness in grapevine

Xu Wang, Zhongjie Liu, Fan Zhang, Hua Xiao, Shuo Cao, Hui Xue, Wénwén Liú, Ying Su, Zhenya Liu, Haixia Zhong, Fuchun Zhang, Bilal Ahmad, Qiming Long, Yingchun Zhang, Yuting Liu, , Yongfeng Zhou

This study identifies the polygenic basis of seedlessness in grapevines using integrative genomics, revealing key genes and a machine learning model with 99% prediction accuracy.

Current Biology · Aug 1, 2024Peer-reviewedGenetics