Author

Yi-Wei Chen

University of California, Los Angeles

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Approach:genetic perturbation / CRISPR· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Asis Das· 2 shared Hung Ton‐ThatiD· 2 shared Aadil Hussain BhatiD· 1 shared Alexis Luu· 1 shared Andreas Tauch· 1 shared Angela AgnewiD· 1 shared Chenggang WuiD· 1 shared Chungyu ChangiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersMicrobiology

Asis Das

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2 papers

Recent·Most cited

Inactivation of the Fusobacterium nucleatum Rnf complex reduces FadA-mediated amyloid formation and tumor development

Timmie A. Britton, Ju Huck Lee, Chungyu Chang, Aadil Hussain Bhat, Yi-Wei Chen, Rusul Mohammed Ali, Chenggang Wu, Asis Das, Hung Ton‐That

This paper shows that disrupting the Rnf complex in Fusobacterium nucleatum reduces FadA amyloid formation and tumor development by affecting signal peptidase expression.

mBio · May 22, 2025Peer-reviewedMicrobiology

Ethanolamine-induced assembly of microcompartments is required for Fusobacterium nucleatum virulence

Dana S. Franklin, Yi-Wei Chen, Yimin Chen, Manuel Wittchen, Angela Agnew, Alexis Luu, Julian P. Whitelegge, Z. Hong Zhou, Andreas Tauch, Asis Das, Hung Ton‐That

This paper shows that ethanolamine utilization via BMCs is essential for Fusobacterium nucleatum virulence, as BMC formation is regulated by a TCS and disruption reduces pathogenicity in a mouse model.

mBio · Dec 23, 2024Peer-reviewedMicrobiology