miR-21-5p and miR-30a-5p are identical in human and bovine, have similar isomiR distribution, and cannot be used to identify xenomiR uptake from cow milk
Bastian Fromm, Juan Pablo Tosar, Yin Lu, Marc K. Halushka, Kenneth Whitaker Witwer
The paper shows miR-21-5p and miR-30a-5p are identical between human and bovine, and their presence in human blood after milk ingestion is likely due to endogenous regulation or technical issues, not xenomiR uptake.
Journal of Nutrition · Jun 19, 2018Peer-reviewedMolecular Biology