Single-cell RNA-seq analysis reveals aberrant CSF1 expression in disease-causing synovial fibroblasts of pigmented villonodular synovitis
Yiyong Tang, Mengjun Ma, Rujia Mi, Wenzhou Liu, Jingyi Hou, Yanjie Feng, Meijun Zhang, Menglei Yu, Fangqi Li, Yihui Song, Yixuan Lu, Yan Yan, Rui Yang
The paper uses scRNA-seq to identify CSF1-expressing fibroblasts in PVNS and their role in attracting macrophages to form disease masses.
bioRxiv · Sep 29, 2021 · PreprintMolecular Biology