Allosteric Biosensors Unravel GTPase-Effector Feedback
Mingyu Choi, Roshan Ravishankar, Lihua He, Yu Yan, Gabriel J Kreider, Pengning Xu, Danielle E Lee, Gaudenz M. Danuser, Klaus M. Hahn
The paper introduces GTPase biosensors that report activity without blocking ligand interactions, revealing feedback mechanisms in Rac1 regulation.
bioRxiv · Oct 29, 2026 · PreprintCell Biology