The effects of DNA repair factor-Cas9 fusions on homing gene drive performance
Yingke Wu, Xuejiao Xu, Nan Liang, Yunchen Xia, Andrea Y.N. Tan, Jie Yang, Xiaozhen Yang, Jackson Champer
This study evaluates Cas9 fusion proteins in Drosophila to enhance homing gene drive performance by improving HDR and reducing resistance.
bioRxiv · Oct 28, 2026 · PreprintGenetics