Author

Yuning Wei

Stanford University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 3 Developmental Biology· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell type annotation· 4 Research Focus:differential expression· 4 Research Focus:gene regulatory network inference· 4 Organism:human· 3 Organism:mouse· 3 Assay:ChIP-seq· 2 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Howard Y. ChangiD· 5 shared Paul A. KhavariiD· 3 shared Rui LiiD· 3 shared Brian J. Zarnegar· 2 shared Diana R. DouiD· 2 shared Hani ChoudhryiD· 2 shared Jin XuiD· 2 shared M. Ryan CorcesiD· 2 shared

Activity by Year

2017-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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5 shared papersGenomics

Howard Y. ChangORCID

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Author profile →

6 papers

Recent·Most cited

Clonal inactivation of telomerase promotes accelerated stem cell differentiation

Kazuteru Hasegawa, Yang Zhao, Alina Garbuzov, M. Ryan Corces, Lü Chen, Peggie Cheung, Yuning Wei, Howard Y. Chang, Steven E. Artandi

This study shows that TERT inactivation accelerates stem cell differentiation and disrupts clone formation, independent of telomere elongation, and links TERT to MYC activity.

bioRxiv · Apr 28, 2021 · PreprintDevelopmental Biology

Structural modularity of the XIST ribonucleoprotein complex

Zhipeng Lu, Jimmy K. Guo, Yuning Wei, Diana R. Dou, Brian J. Zarnegar, Qing Ma, Rui Li, Yang Zhao, Fan Liu, Hani Choudhry, Paul A. Khavari, Howard Y. Chang

The paper demonstrates that the XIST RNA-protein complex has a modular architecture that determines RBP binding and m6A modification, beyond sequence motifs.

Nature Communications · Dec 2, 2020Peer-reviewedMolecular Biology

Spen links RNA-mediated endogenous retrovirus silencing and X chromosome inactivation

Ava C. Carter, Jin Xu, Meagan Y Nakamoto, Yuning Wei, Brian J. Zarnegar, Quanming Shi, James P. Broughton, Ryan C. Ransom, Ankit Salhotra, Surya Nagaraja, Rui Li, Diana R. Dou, Kathryn E. Yost, Seung-Woo Cho, Anil Mistry, , Howard Y. Chang

This study shows Spen binds to endogenous retroviral RNAs and recruits chromatin silencing machinery, linking RNA-mediated retrovirus silencing to X chromosome inactivation.

eLife · May 7, 2020Peer-reviewedGenomics

Single-Cell RNA-Seq Reveals Endocardial Defect in Hypoplastic Left Heart Syndrome

Yifei Miao, Lei Tian, Marcy Martin, Sharon L. Paige, Francisco X. Galdos, Jibiao Li, Alyssa Guttman, Yuning Wei, Jan-Renier A. J. Moonen, Hao Zhang, Ning Ma, Bing Zhang, Paul Grossfeld, Seema R. Mital, David A. Chitayat, , Mingxia Gu

This study uses single-cell RNA sequencing to identify endocardial defects in hypoplastic left heart syndrome, linking them to abnormal valve and septum development.

bioRxiv · Oct 17, 2019 · PreprintDevelopmental Biology

Joint single-cell DNA accessibility and protein epitope profiling reveals environmental regulation of epigenomic heterogeneity

Xingqi Chen, Ulrike M. Litzenburger, Yuning Wei, Alicia N. Schep, Edward L. LaGory, Hani Choudhry, Amato J. Giaccia, William James Greenleaf, Howard Y. Chang

The paper introduces Pi-ATAC, a method combining single-cell chromatin and proteomic profiling, revealing hypoxia's role in shaping the regulome in tumor cells.

Nature Communications · Oct 29, 2018Peer-reviewedGenomics

Enhancer connectome in primary human cells reveals target genes of disease-associated DNA elements

Maxwell R. Mumbach, Ansuman T. Satpathy, Evan A. Boyle, Chao Dai, Benjamin G. Gowen, Seung Woo Cho, Michelle Ly Thai Nguyen, Adam J. Rubin, Jeffrey M. Granja, Katelynn R. Kazane, Yuning Wei, Trieu Nguyen, Peyton Greenside, M. Ryan Corces, Josh Tycko, , Howard Y. Chang

This paper uses HiChIP to map enhancer-promoter interactions in primary human cells, linking disease-associated DNA variants to their target genes.

Nature Genetics · Sep 25, 2017Peer-reviewedGenomics