Truncation of poly-N-acetylglucosamine (PNAG) polymerization with N-acetylglucosamine analogues
Z. Morrison, A. Eddenden, A. S. Subramanian, P. L. Howell, m. nitz
The paper identifies UDP-GlcNAc analogues that inhibit PNAG polymerization and biofilm formation in E. coli by terminating PNAG chains.
bioRxiv · Oct 13, 2021Biochemistry