Author

Zezhen Lu

Zhejiang University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Assay:scRNA-seq· 2 Research Focus:batch correction / integration· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Assay:snRNA-seq· 1

Frequent Co-Authors

Chaochen WangiD· 1 shared Jingyi Jessica LiiD· 1 shared Ken-ichi MizutaniiD· 1 shared Li SheniD· 1 shared Marina Takechi· 1 shared Shinpei YamaguchiiD· 1 shared Tianyi SuniD· 1 shared Toru NakanoiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperBioinformatics

Chaochen WangORCID

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2 papers

Recent·Most cited

Parthenogenote-Derived Brain Unveils the Critical Role of Paternal Genome in Neural Development

Marina Takechi, Yezhang Zhu, Zezhen Lu, Ying Zeng, Ken-ichi Mizutani, Toru Nakano, Li Shen, Shinpei Yamaguchi

This study uses a novel cell replacement strategy to show that the paternal genome is critical for neural development through Dlk1-mediated regulation of Notch signaling.

Scientific Reports · Jun 8, 2026Peer-reviewedDevelopmental Biology

scCDC: a computational method for gene-specific contamination detection and correction in single-cell and single-nucleus RNA-seq data

Weijian Wang, Yihui Cen, Zezhen Lu, Yueqing Xu, Tianyi Sun, Ying Xiao, Wanlu Liu, Jingyi Jessica Li, Chaochen Wang

scCDC detects and corrects contamination in scRNA-seq and snRNA-seq data by identifying contamination-causing genes, achieving better accuracy than existing methods.

Genome biology · May 23, 2024Peer-reviewedBioinformatics