Structural basis of nucleosome recognition by the human NuA4/TIP60 acetyltransferase complex
Zhenlin Yang, Alfredo Jose Florez Ariza, Jacques Cote, Eva Nogales
This study presents the structure of the human TIP60-C HAT module bound to a nucleosome, revealing how it positions the catalytic center on the nucleosome surface and engages the linker DNA.
bioRxiv · Nov 4, 2026 · PreprintBiophysics