Author

Zhigao Chen

Chinese Academy of Medical Sciences & Peking Union Medical College

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:spatial transcriptomics· 1 Assay:whole-exome sequencing· 1

Frequent Co-Authors

Bin XiaoiD· 1 shared Fangze Qian· 1 shared Gao WentaoiD· 1 shared Han LiangiD· 1 shared Hao Yuan· 1 shared Jianzhen Lin· 1 shared Jing Zhou· 1 shared Jishu WeiiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Bin XiaoORCID

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1 paper

Recent·Most cited

Co-evolution of Oncogenic KRAS Signaling and LILRBhigh Macrophages Drives Pancreatic Cancer Recurrence

Jianzhen Lin, Zhenzhen Xun, Fangze Qian, Zhigao Chen, Weikang Hu, W. Liu, Yang Wu, Hao Yuan, Lingdi Yin, Yuxing Wang, Xiao Huang, Yujia Dang, Bin Xiao, Junli Wu, Gao Wentao, , Han Liang

This study identifies a co-evolved tumor-immune interaction involving KRAS signaling and LILRBhigh macrophages that drives PDAC recurrence and presents a therapeutic strategy targeting this axis.

bioRxiv · Mar 7, 2026 · PreprintCancer Biology