Author

Zhiyi Chen

China Agricultural University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Neuroscience· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:chromatin & epigenetic regulation· 2 Approach:experimental assay· 2 Organism:Arabidopsis· 1 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Ancély Ferreira dos SantosiD· 1 shared Anna Schmitt· 1 shared Apoorva MathuriD· 1 shared Ariadne Androulidaki· 1 shared Ariane Nunes‐AlvesiD· 1 shared Armin Khonsari· 1 shared Ben Clayden· 1 shared Bettina PronethiD· 1 shared

Activity by Year

2021-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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1 shared paperCell Biology

Ancély Ferreira dos SantosORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Riboflavin metabolism shapes FSP1-driven ferroptosis resistance

Vera Skafar, Izadora de Souza, Biplab Ghosh, Ancély Ferreira dos Santos, Florêncio Porto Freitas, Zhiyi Chen, Shibo Sun, Merce Donate Castillo, Palina Nepachalovich, Lars Seufert, Sebastian Bothe, Juliane Tschuck, Apoorva Mathur, Ariane Nunes‐Alves, Jannik Buhr, , José Pedro Friedmann Angeli

This study identifies riboflavin as a modulator of ferroptosis sensitivity by supporting FSP1 stability and antioxidant recycling, with implications for therapeutic targeting.

bioRxiv · Aug 5, 2025Cell Biology

Reversible ubiquitination of integrated domain controls paired NLR immune receptor complex homeostasis

Zhiyi Chen, Jianhua Huang, Jian-Yu Li, Frank L.H. Menke, Jonathan D. G. Jones, Hailong Guo

The paper identifies a ubiquitination-deubiquitination cycle regulating the stability and function of the paired NLR receptor complex RRS1/RPS4 in Arabidopsis.

Nature Communications · Feb 26, 2025Peer-reviewedPlant Biology

Theta oscillations tag memories for sleep-dependent consolidation

Dan Denis, Zhiyi Chen, M Kaur, Ben Clayden, Thomas Schreiner, Scott A. Cairney

The paper identifies theta oscillations as a mechanism for tagging memories during learning, which predicts sleep-dependent consolidation through coupling with slow oscillations and sleep spindles.

bioRxiv · Jan 25, 2025 · PreprintNeuroscience

Ferroptosis response segregates small cell lung cancer (SCLC) neuroendocrine subtypes

Christina Bebber, Emily Thomas, Zhiyi Chen, Jenny Stroh, Ariadne Androulidaki, Anna Schmitt, Michaela Hoehne, Lukas Stueker, Marcel Dammert, Fatma Parmaksiz, Cleidson de Padua Alves, Armin Khonsari, Filippo Beleggia, Martin Sos, Jan Riemer, , Silvia von Karstedt

The paper identifies ferroptosis sensitivity as a distinguishing feature of non-neuroendocrine SCLC subtypes and shows that combining ferroptosis induction with TRX pathway inhibition can selectively kill both non-NE and NE SCLC tumors.

Nature Communications · Apr 6, 2021Peer-reviewedCancer Biology