Cancer BiologyNature CommunicationsPeer-reviewed
Ferroptosis response segregates small cell lung cancer (SCLC) neuroendocrine subtypes
Christina Bebber, Emily Thomas, Zhiyi Chen…·Silvia von Karstedt
The paper identifies ferroptosis sensitivity as a distinguishing feature of non-neuroendocrine SCLC subtypes and shows that combining ferroptosis induction with TRX pathway inhibition can selectively kill both non-NE and NE SCLC tumors.
DOI 10.1038/s41467-021-22336-4