Author

Zichen Gao

Harvard University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Research Focus:benchmarking· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:proteomics· 1

Frequent Co-Authors

Christopher M MadliD· 1 shared Dina L. BaiiD· 1 shared Erik Hultenius· 1 shared Erin D. JefferyiD· 1 shared Gregory R. KeeleiD· 1 shared Haiying Hu· 1 shared João A. PauloiD· 1 shared Ping Zhou· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBioengineering

Christopher M MadlORCID

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2 papers

Recent·Most cited

Tissue-like Viscoelasticity Drives Muscle Stem Cell Expansion Through Mechanical Memory Formation

Haiying Hu, Tae Yoon Kwon, Zichen Gao, Ping Zhou, Christopher M Madl

This study shows that tissue-like viscoelastic substrates enhance muscle stem cell expansion by creating mechanical memory through focal adhesion stabilization and Rac-Akt signaling.

bioRxiv · Nov 9, 2026 · PreprintBioengineering

Expanding the Landscape of Aging via Orbitrap Astral Mass Spectrometry and Tandem Mass Tag (TMT) Integration

Gregory R. Keele, Yue Dou, Seth P. Kodikara, Erin D. Jeffery, Dina L. Bai, Erik Hultenius, Zichen Gao, João A. Paulo, Steven P. Gygi, Xiao Yan Tian, Tian Zhang

This study uses Orbitrap Astral mass spectrometry with TMT to analyze proteomic changes in mouse brain and kidney tissues across age and sex, revealing tissue-specific and non-linear age-related protein dynamics.

Nature Communications · May 22, 2025Peer-reviewedSystems Biology