Author

Zuofan Wu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 2

Signature Assays, Organisms & Methods

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Assay:protein structure· 2 Research Focus:protein structure prediction· 2 Approach:deep learning· 1 Assay:protein sequence· 1 Approach:statistical model· 1 Approach:transformer / foundation model· 1

Frequent Co-Authors

Chenpeng Su· 2 shared Jian PengiD· 2 shared Jianzhu MaiD· 2 shared Shitong LuoiD· 2 shared Bonnie BergeriD· 1 shared Fan DingiD· 1 shared Qi XieiD· 1 shared Rui SheniD· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBioinformatics

Chenpeng Su

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2 papers

Recent·Most cited

Rotamer Density Estimator is an Unsupervised Learner of the Effect of Mutations on Protein-Protein Interaction

Shitong Luo, Yufeng Su, Zuofan Wu, Chenpeng Su, Jian Peng, Jianzhu Ma

The paper introduces RDE, an unsupervised method that predicts mutation effects on protein-protein binding by estimating conformational flexibility from protein structures, outperforming existing methods.

bioRxiv · Feb 28, 2023 · PreprintBioinformatics

High-resolution de novo structure prediction from primary sequence

Ruidong Wu, Fan Ding, Rui Wang, Rui Shen, Xiwen Zhang, Shitong Luo, Chenpeng Su, Zuofan Wu, Qi Xie, Bonnie Berger, Jianzhu Ma, Jian Peng

From a single sequence, OmegaFold reaches mean LDDT 0.82 on 146 CAMEO targets, between MSA-based RoseTTAFold (0.75) and AlphaFold2 (0.86), and runs about ten times faster.

bioRxiv · Jul 21, 2022 · PreprintBioinformatics✦ In-depth digest