Tanya Vavouri

High piRNA abundance is a hallmark of evolutionarily persistent piRNA-producing loci.

The paper identifies high piRNA abundance as a key feature of evolutionarily persistent piRNA-producing loci across mouse and primate species.

Genetic polymorphisms lead to major, locus-specific, variation in piRNA production in mouse.

The paper analyzes piRNA expression variation across mouse strains and finds genetic differences contribute to strain-specific piRNA production, including from retrovirus insertions and protein-coding genes.

Intergenerational metabolic priming by sperm piRNAs

This study shows that paternal dietary sugar affects offspring gene expression through sperm piRNA pathways, linking small RNA regulation to intergenerational epigenetic inheritance.

Assessment of kinship detection using RNA-seq data.

This study evaluates using RNA-seq data to detect kinship by estimating pairwise identity-by-descent, showing it can identify up to second-degree relationships with low to moderate sequencing depth.

The Polycomb-dependent epigenome controls β-cell dysfunction, dedifferentiation and diabetes

This study identifies chromatin-state signatures linked to β-cell dysfunction and diabetes by combining epigenome mapping with single-cell transcriptomics in mice and humans.