bioRxivMicrobiologyPreprint
Reduced Lytic Activity of Bacteriophages in Presence of Antibiotics Targeting Bacterial Protein Synthesis
M. Vashisth, S. Yashveer, N. Virmani, B. C. Bera, R. K. Vaid, T. Anand
Abstract
Combination therapy of bacteriophage and antibiotics offers promise to treat multiple drug resistant bacterial infections through phage antibiotic synergy. However, its usage requires careful assessment as most antibiotics with mechanisms dependent upon inhibiting cell growth through interfering bacterial protein synthesis machinery were found to have an antagonistic effect on phage activity.
- organism: bacteria (other)
- research focus: host-pathogen & immune response
- approach: experimental assay
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