DPYD links glial lipids and myelination to sleep duration
Amber J Zimmerman, Samantha Deal, Erika Almeraya Del Valle, Joshua Donnelly, Francois Kroll, Xiaofeng Guo, Trisha Tsundupalli, Zoe Shetty, Fusun Doldur-Balli, Brendan Keenan, Struan FA Grant, Jason Rihel, Amita Sehgal, Allan I Pack
This study identifies DPYD's role in sleep regulation through glial lipid metabolism and myelination across species, linking genetic variants to oligodendrocyte-specific control.
bioRxiv · Nov 3, 2026 · PreprintNeuroscience