Bone Tissue Engineering Materials

This paper develops a nanohydroxyapatite-alginate composite scaffold with dual drug release for dental tissue engineering, showing improved biocompatibility and osteogenesis.

This study shows that polyanionic NCPs and their analogues promote artificial mineralization in embryonic mouse bone ECM by facilitating apatite infiltration into collagen fibrils.

This study examines how fetuin-A affects osteoblast-like cell attachment and proliferation on gold surfaces, finding it enhances adhesion but limits proliferation compared to fibronectin.

This paper demonstrates that 2D boron nanoplatelets enhance osteogenesis, anti-microbial properties, and mechanical strength in collagen scaffolds for bone repair.

This study uses liquid TEM to visualize the three-step mineralization process of calcium phosphate on titanium dioxide nanoparticles, revealing dynamic structural changes and electron beam effects.

This study shows HIF-1α enhances osteogenic-angiogenic coupling in BMSCs cell sheets, promoting bone formation and vascular network development in vitro.

This paper develops a novel biomaterial, My-ALG-HA, using Ganoderma sessile mycelium to enhance bone tissue regeneration by improving structural integrity and biological functionality.

This study shows that controlled delivery of immunomodulatory factors can enhance MSC osteogenesis and modulate inflammation in both in vitro and in vivo models of chronic inflammation.

This paper develops a zinc and metformin functionalized PEEK dental implant material to improve osseointegration in elderly patients by addressing osteogenic potential, inflammation, and cell senescence.

This study develops ECM-decorated biodegradable scaffolds as synthetic periosteal grafts, showing improved cell growth and angiogenic effects in vitro.

The paper develops an ex vivo chick embryonic bone model using PLGA microparticles to study growth factor delivery effects on cell differentiation and tissue formation, showing that controlled release of BMP2 and FGF2 alters collagen deposition and cell morphology.

This paper develops an injectable GelMA hydrogel with MSN-mediated spatiotemporal Icariin release to enhance osseointegration in bone defects.

This paper introduces a topography-driven platform for stem cell differentiation without biochemical cues, showing it induces osteogenesis through mechanotransduction and Hedgehog signaling.

This study evaluates MC-GAG scaffolds with PDLLA fixation for cranial defect regeneration, finding enhanced bone mineralization and mechanical properties compared to controls.

This paper uses bibliometric analysis to map the evolution of immunomodulatory biomaterials in implant osseointegration from 2005 to 2025, identifying key trends and future directions.

This study evaluates the impact of calcium pyrophosphate on heterotopic bone formation and quality using calcium phosphate materials in sheep.

This study develops modular, vascularized hypertrophic cartilage constructs for bone tissue engineering that support simultaneous mineralization and vessel formation without exogenous supplements.

This study develops a composite scaffold combining 3D-printed HA-WOL lattices with chitosan-gelatin cryogels, showing improved mechanical properties and bioactivity for bone tissue engineering.

This study examines how adding P2O5 affects the structure, crystallization, and bioactivity of silicate-based bioactive glasses and glass-ceramics, finding it enhances bioactivity but delays ion release in glass-ceramics.

This paper develops a nitinol lumbar vertebral implant using braiding techniques to enhance both mechanical and biological properties, showing biocompatibility and suitable surface characteristics.

The paper develops novel biomolecular techniques to image and analyze orthopaedic trabecular metal implants, showing varying responses of human bone marrow stem cells to different implant designs.

This study tests the BioAxFlow bioreactor's ability to enhance cell adhesion, proliferation, and maintain osteogenic and tumorigenic properties of SAOS-2 cells in a dynamic culture system.

This study characterizes the extracellular matrix (ECM) produced by MC3T3-E1 spheroids in alginate hydrogel, showing collagen deposition between week 2 and 4.

This study evaluates silica and bioglass nanomaterials in a pulp-like model, finding that bioglass supports cell metabolism and homogenous distribution while silica has mixed effects.

This study develops antimicrobial scaffolds to protect BM-MSC-based implants from bacterial infections, showing effective inhibition of bacterial growth and enhanced bone regeneration in vivo.

This study investigates how bone-derived nanoparticles (BNPs) enhance osteogenic differentiation of mesenchymal stem cells (MSCs) through Notch signaling, specifically by increasing Dll4 expression.

This study uses XGBoost and SHAP to predict and interpret PLGA scaffold biocompatibility based on mechanical and structural properties, identifying key factors influencing cell adhesion and tissue integration.

This study investigates JAG1 delivery with pediatric human osteoblasts as a bone regenerative therapy for craniofacial defects in a murine model.

This paper fabricates graphene oxide-reinforced 13-93B1 bioactive glass scaffolds using direct ink writing and evaluates their mechanical, structural, and biological properties for bone tissue engineering.

This paper presents a 3D-printed composite scaffold system for bone regeneration that accelerates ECM and mineralized osteoid deposition in vivo.