Felicity R. A. J. Rose

This paper develops a co-differentiation platform using human iPSCs to generate transplantable colonic tissue that mimics native mucosa and responds to biological signals.

The paper develops an ex vivo chick embryonic bone model using PLGA microparticles to study growth factor delivery effects on cell differentiation and tissue formation, showing that controlled release of BMP2 and FGF2 alters collagen deposition and cell morphology.

This study evaluates Laponite(R)-coated scaffolds for delivering BMP-2 in a large animal bone defect model, showing enhanced bone formation compared to uncoated scaffolds.

This study develops human gut models to investigate interactions between anaerobic bacteria and the gut epithelium, showing C. difficile adhesion, spore production, and reduced growth in the presence of B. dorei.